AMBICA PHARMA
Thalidomide

Thalidomide

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WARNING: THALIDOMIDE SHOULD NEVER BE TAKEN BY PREGNANT WOMEN OR WOMEN CAPABLE OF BECOMING PREGNANT AS EVEN A SINGLE DOSE CAN CAUSE SEVERE BIRTH DEFECTS OR DEATH TO AN UNBORN BABY.

PLEASE REFER TO PATIENT INFORMATION SHEET FOR DETAILED INSTRUCTIONS FOR PATIENTS.

COMPOSITON:

Zuvimide -100

Each Capsule contains:

Thalidomide USP.................................. 100 mg.

Zuvimide -50

Each Capsule contains:

Thalidomide USP.................................. ..50 mg.

Description

Thalidomide is an immunomodulatory agent with a promising activity against a variety of tumors and cutaneous manifestations of Erythema NodosumLeprosum (ENL). Thalidomide is an off-white to white, nearly odorless, crystalline powder that is soluble at 25°C in dimethyl sulfoxide and sparingly soluble in water and ethanol. The glutarimide moiety contains a single asymmetric center and therefore, may exist in either of two optically active forms designated S-(-) or R - (+) Thaildomide is an equal mixture of the S-(-) forms and R-(+) forms and, therefore, has a net optical rotation of zero.

CHEMISTRY

Thalidomide is a (N-phthalimido) glutarimide. The empirical formula for thalidomide is C13H10N2O4 and the gram molecular weight is 258.2. Chemical Structure Of Thalidomid