AMBICA PHARMA
Methylcobalamine

Methylcobalamine

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We feel immense pleasure to introduce ourselves as one of the leading manufacturers and suppliers of an excellent stock of Methylcobalamin. Also known as Methyl-B12 or Mecobalamin, this medicine is a form of the common vitamin B12. Methylcobalamin is widely used as a dietary supplement and for the treatment of certain anemias. Differs from typical B12 in that it has an additional methyl group, this medicine also contains metal-alkyl bonds.

Key points:

  • Plays an important role in helping the body make red blood cells
  • Possess neuro-protective
  • Loaded with anti- aging properties

 

Methylcobalamine-1500mcg+Alpha Lipoic Acid-100mg Tablet

 

Methylcobalamin (mecobalamin, MeCbl, or MeB12) is a cobalamin, a form of vitamin B12. It differs from cyanocobalamin in that the cyano at the cobalt is replaced with a methyl group.[1] Methylcobalamin features an octahedral cobalt(III) centre and can be obtained as bright red crystals.[2] From the perspective of coordination chemistry, methylcobalamin is notable as a rare example of a compound that contains metal-alkyl bonds. Nickel-methyl intermediates have been proposed for the final step of methanogenesis.

Methylcobalamin is equivalent physiologically to vitamin B12, and can be used to prevent or treat pathology arising from a lack of vitamin B12 (vitamin B12 deficiency), such as pernicious anemia.

Methylcobalamin is also used in the treatment of peripheral neuropathy, diabetic neuropathy, and as a preliminary treatment for amyotrophic lateral sclerosis.[3]

Methylcobalamin that is ingested is not used directly as a cofactor, but is first converted by MMACHC into cob(II)alamin. Cob(II)alamin is then later converted into the other 2 forms, adenosylcobalamin and methylcobalamin for use as cofactors. That is, methylcobalamin is first dealkylated and then regenerated.[4][5][6]

One author says it is important to treat vitamin B12 deficiency with hydroxocobalamin or cyanocobalamin or a combination of adenosylcobalamin and methylcobalamin, and not methylcobalamin alone.[7]