Aqueous Injection Each ml of Zeflo 250/500 mg Injection contains:
As Fluorouracil Sodium 50mg
Fluorouracil Injection, an antineoplastic antimetabolite, is a sterile, nonpyrogenic injectable solution for intravenous administration. Each mL contains 50 mg fluorouracil in water for injection, pH is adjusted to approximately 9.2 with sodium hydroxide.
Chemically, fluorouracil, a fluorinated pyrimidine, is 5-fluoro-2,4 (1H,3H)-pyrimidinedione. It is a white to practically white crystalline powder which is sparingly soluble in water. The molecular weight of fluorouracil is 130.08
Fluorouracil is indicated in the palliative treatment of carcinoma of the colon, rectum, breast, stomach and pancreas.